Iatrogenic transmission of Creutzfeldt-Jakob disease

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Iatrogenic transmission of Creutzfeldt-Jakob disease.

Creutzfeldt-Jakob disease is a rare progressive neurological disorder which is eventually fatal. Attention has recently been focused upon the iatrogenic transmission of this disease by four published reports of patients developing Creutzfeldt-Jakob disease associated with the administration of human growth hormone preparations originally prepared from human cadaver pituitaries. Characterized cl...

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Iatrogenic Creutzfeldt-Jakob Disease, Final Assessment

The era of iatrogenic Creutzfeldt-Jakob disease (CJD) has nearly closed; only occasional cases with exceptionally long incubation periods are still appearing. The principal sources of these outbreaks are contaminated growth hormone (226 cases) and dura mater grafts (228 cases) derived from human cadavers with undiagnosed CJD infections; a small number of additional cases are caused by neurosurg...

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Creutzfeldt-Jakob disease: A case report

Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...

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Lingering Doubts about Creutzfeldt-Jakob disease: Mode of transmission Running Title: Creutzfeldt-Jakob disease

Based on clinical and pathological observation Creutzfeldt-Jakob disease (CJD) been classified into three groups: (1) Familial: (2) Iatrogenic: (3) Sporadic: Shortly after the appearance of bovine spongiform encephalopathy (BSE), CJD a disease normally seen in older patients was identified in young patients with non-classical presentation. It now appears that patients all age groups have died o...

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Iatrogenic Creutzfeldt-Jakob disease: the waning of an era.

The outbreaks of iatrogenic Creutzfeldt-Jakob disease (CJD) from cadaveric human growth hormone and dura mater are winding down and, like the only other environmentally acquired form of CJD (variant CJD due to infection with the agent of bovine spongiform encephalopathy), iatrogenic disease seems to have reached its high water mark during the 1990s. The total number of cases has reached 405, an...

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ژورنال

عنوان ژورنال: Psychological Medicine

سال: 1989

ISSN: 0033-2917,1469-8978

DOI: 10.1017/s0033291700010965